Genitourinary Cancers   

Would surgical margins, evidence of angiolymphatic spread, number of lymph nodes removed during surgery inform your decision? 

How reliable is somatic testing to detect an underlying germline predisposition?

If serum markers were normal, how strongly do you consider 1 cycle of BEP for embryonal predominant pathology? 

VIP can be considered, but given complex psychosocial issues and limited community cancer treatment resources, this question is being asked. 

NCCN guidelines state check at baseline and then as clinically indicated. Some other sources state, can check prior to each cycle of BEP?  What ...

Given persistent embryonal histology on RPLND, do you favor observation or TIP/VIP? What do you use to guide your decision?

Would you have reservations in treating patients with breast, GI, or pelvic malignancies with radiation alone or concurrent chemoradiation?

GI work up negative. NGS cancer type and isochromosome 12p ordered and pending. Pathology at RPLND was negative for cancer.