Pediatric Oncology

Thrombocytopenia   

Questions discussed in this category



I.e. platelet count <30. Would your management change if HIT were only suspected rather than confirmed?  

Provided that the platelet count is normal, do you usually consider this to be a potential erroneous result or do you pursue additional workup for RBC...

Such as the case in which a patient is unresponsive to steroids, IVIG, TPO-agonist, rituximab, splenectomy, and even fostamitinib.

How often do you monitor ADAMTS-13 levels off therapy?

For example, do we prefer one regimen over the other in patients with a bleeding history or who have relapsed after a lengthy remission?


Papers discussed in this category


Blood, 2021 Apr 01

Blood, 2018 Sep 10