Radiation Oncology

Gastroesophageal Cancer

Questions discussed in this category

How do you treat locally advanced, operable, Siewert 3 GE junction adenocarcinomas?

3 Answers available

Would you offer local therapy to a patient with GEJ adenocarcinoma with FDG-avid para-aortic node oligometastasis?

For nodes just inferior to the celiac/SMA axis and no other distant metastatic disease? Stage is formally M1, but just barely. The patient is otherwis...

2 Answers available

How do you select neoadjuvant chemo vs chemoRT in locally advanced, resectable GEJ/esophageal tumors?

NCCN recommends perioperative FLOT or FOLFOX vs. neoadjuvant chemoRT with Carboplatin/Paclitaxel or FOLFOX.Does CM-577 and the approval of nivolumab p...

9 Answers available

Can the results of Checkmate 577 be applied to patients who do not undergo surgery following chemoradiation because of a clinical complete response?

What about for a patient with complete radiographic response who declines surgical management?

3 Answers available

How would you treat a patient with adenocarcinoma of the GE junction in the setting of interstitial lung disease?

Is neoadjuvant chemoradiation or perioperative chemotherapy preferred?

1 Answer available

Do you recommend adjuvant chemoradiation for T2N0 gastric adenocarcinoma?

In a patient with an R0 resection, would you routinely recommend postop chemoradiation, since these patients were included in the MacDo...

1 Answer available

Papers discussed in this category

Annals of surgical oncology, 2016-11

What's the Best Way to Treat GE Junction Tumors? Approach Like Gastric Cancer.

The Journal of thoracic and cardiovascular surgery, 2007 Aug

Lymph node involvement in advanced gastroesophageal junction adenocarcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012-07-01

Updated analysis of SWOG-directed intergroup study 0116: a phase III trial of adjuvant radiochemotherapy versus observation after curative gastric cancer resection.

The New England journal of medicine, 2001-09-06

Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction.

Lancet Oncol., 2015-09-01

Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial.

N Engl J Med, 2006 Jul 6

Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer.

The New England journal of medicine, 2002-10-17

Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.

Ann. Surg., 2007-11-01

The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma.

N Engl J Med, 2021-04-01

Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer.

J Clin Oncol, 2021 Apr 23

Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial.

Lancet,

Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co-ordinating Committee on Cancer Research.

BMC Cancer, 2016 Jul 19

ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant chemoradiation (CROSS protocol) in patients with adenocarcinoma of the esophagus (NCT02509286).

Int J Radiat Oncol Biol Phys, 2022 Jul 04

A Critical Review of the Role of Local Therapy for Oligometastatic Gastrointestinal Cancer.

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