Rheumatology

Scleroderma

Questions discussed in this category

How do you counsel patients on the use of topical nitroglycerin for Raynaud's?

What formulation of topical nitroglycerin do you use?

What would be your approach to a patient with Scleroderma/Myositis overlap syndrome (+anti-Ku) and active inflammatory eye disease despite high dose mycophenolate?

2 Answers available

How would you approach management of a patient with rapidly progressive systemic sclerosis with worsening skin disease, myositis, arthritis, dysphagia and failure to thrive developing within 6 months?

The patient is a young African American female of reproductive age with positive Fibrillarin antibody and nucleolar antibody. No ILD.

1 Answer available

How do you approach management of a patient with idiopathic PAH and +ANA, but no other current symptoms/signs of active rheumatologic disease?

3 Answers available

Is morphea, cutaneous scleroderma, with no organ involvement a contraindication for radiation in early stage breast cancer as part of breast conservation therapy?

3 Answers available

How do you manage patients with systemic sclerosis and chronic thrombotic microangiopathy on renal biopsy, but no other evidence of scleroderma renal crisis?

Patient with nephrotic range proteinuria, but there is no evidence of active TMA on renal biopsy.

1 Answer available

When is a kidney biopsy warranted in a patient with possible scleroderma renal crisis?

1 Answer available

How would you manage scleritis perforans in a patient with seropositive rheumatoid arthritis/scleroderma overlap?

Patient has failed methotrexate and adalimumab.

2 Answers available

Would you feel comfortable combining MMF and an IL-17 blocker in a patient with both limited scleroderma and psoriatic arthritis?

2 Answers available

How do you monitor a patient with scleroderma during pregnancy?

1 Answer available

When do you consider vascular imaging in patients with Raynaud's and what type of imaging modalities do you utilize?

1 Answer available

Is there a role for cyclophosphamide in refractory digital ischemia in patients with scleroderma?

1 Answer available

How do you utilize methotrexate and/or hydroxychloroquine in the setting of limited scleroderma/CREST?

1 Answer available

What criteria do you use on echocardiogram and PFT to determine who needs further evaluation for CTD-associated pulmonary hypertension?

1 Answer available

Papers discussed in this category

Eur Heart J, 2015 Aug 29

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).

Eur Respir J, 2019 Jan 24

Diagnosis of pulmonary hypertension.

The Lancet. Respiratory medicine, 2016-09

Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial.

Case reports in rheumatology, 2017

A Rare Case of Digital Ischemia and Gangrene in ANCA-Associated Vasculitis with Review of the Literature.

Arthritis Rheum,

Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud's phenomenon to systemic sclerosis: a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis.

Arthritis care & research, 2018-10

Impact of Radiation Therapy on Scleroderma and Cancer Outcomes in Scleroderma Patients With Breast Cancer.

Breast Care (Basel), 2019 Aug 16

Incidence of Morphea following Adjuvant Irradiation of the Breast in 2,268 Patients.

Annals of clinical and laboratory science, 2008

Nephrotic range proteinuria: rare manifestation of scleroderma renal crisis.

International journal of general medicine, 2019 Sep 02

Renal pathology and clinical associations in systemic sclerosis: a historical cohort study.

Rheumatology

Scleroderma

Questions discussed in this category

Papers discussed in this category

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