Hematology

Critical Care

Questions discussed in this category

What is your approach to iron supplementation in patients with an active infection?

Are there situations in which you still feel comfortable giving IV iron? If not, do you consider PO iron?

1 Answer available

How do you decide whether to use pharmacologic VTE prophylaxis in hospitalized patients with decompensated cirrhosis?

How do factors like the presence of varices, severity of coagulopathy, etc., play into your decision?

2 Answers available

What is your approach to VTE prophylaxis in hospitalized patients who are already on DAPT?

Particularly with prolonged hospitalizations, do you have any concerns about exposing patients to bleeding risks associated with "triple therapy" even...

1 Answer available

Do you consider thrombocytopenia a contraindication for fibrinolytic therapy for a massive PE?

Does your platelet threshold (if it exists) differ between Catheter Directed Thrombolysis (CDT) vs. Intravenous Systemic Thrombolysis (IVT)?

2 Answers available

How do you manage concurrent non-life-threatening hemoptysis and acute pulmonary embolism?

Estimating blood loss from hemoptysis is not always reliable. The bleeding may be due to the PE itself. Is anticoagulation with any degree of hemoptys...

1 Answer available

In massive transfusion protocol from suspected hemorrhage, is it worth obtaining a TEG to guide transfusion?

1 Answer available

In which cases would you consider early transition to DOAC (within 72 hours) for hospitalized patients with intermediate or high risk PE?

Assume thrombolytics are not indicated. Do you favor early DOAC transition after 24-48 hours of heparin gtt or do you favor LMWH for 10-14 days follow...

2 Answers available

For patients with suspected complement-mediated TMA, are there specific clinical or laboratory parameters that can help guide the decision for starting empirical treatment (e.g., eculizumab) while awaiting the results of complement testing?

1 Answer available

Are SCDs contraindicated in patients with acute DVTs?

Is it different than early mobility that we always encourage?

3 Answers available

Do you use FVIII levels to differentiate between DIC and coagulopathy of liver disease?

Common thought is that FVIII may be used for differentiating coagulopathy in liver disease (normal to increased, from reduced clearance of VWF/FVIII) ...

4 Answers available

Papers discussed in this category

Hepatology, 1996 Jun

Coagulation factor V levels as a prognostic indicator in fulminant hepatic failure.

Hepatology, 1986 Jul-Aug

Multivariate analysis of prognostic factors in fulminant hepatitis B.

Gut, 1992 Jan

Coagulation factor V and VIII/V ratio as predictors of outcome in paracetamol induced fulminant hepatic failure: relation to other prognostic indicators.

Journal of hospital medicine, 2019-01

Things We Do for No Reason: Intermittent Pneumatic Compression for Medical Ward Patients?

The New England journal of medicine, 2019 Feb 18

Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis.

Phlebology, 2020 Mar 02

Risks and contraindications of medical compression treatment - A critical reappraisal. An international consensus statement.

VASA. Zeitschrift fur Gefasskrankheiten, 2001 Jul

Therapy of deep vein thrombosis with low molecular weight heparin, leg compression and immediate ambulation.

Journal of vascular surgery, 2000 Nov

Compression and walking versus bed rest in the treatment of proximal deep venous thrombosis with low molecular weight heparin.

Respirology (Carlton, Vic.), 2018 Jul 16

Pulmonary infarction: A disease of the (mostly) young.

The Lancet. Haematology, 2021 Aug 04

Early switch to oral anticoagulation in patients with acute intermediate-risk pulmonary embolism (PEITHO-2): a multinational, multicentre, single-arm, phase 4 trial.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2023 Jan-Dec

Retrospective Analysis of Direct-Acting Oral Anticoagulants (DOACs) Initiation Timing and Outcomes After Thrombolysis in High- and Intermediate-Risk Pulmonary Embolism.

Journal of thrombosis and haemostasis : JTH, 2010 Nov

A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score.

Journal of thrombosis and haemostasis : JTH, 2022 Aug 10

Thromboprophylaxis for venous thromboembolism prevention in hospitalized patients with cirrhosis: Guidance from the SSC of the ISTH.

American journal of hematology, 2024 Jan 29

Expert consensus guidelines: Intravenous iron uses, formulations, administration, and management of reactions.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2024 Jun 12

AGA Clinical Practice Update on Management of Iron Deficiency Anemia: Expert Review.

American family physician, 2022 Sep

Risk of Infection With Intravenous Iron Infusion.

Journal of the American College of Cardiology, 2024 Jun 25