Neurology

Pediatric Oncology

Questions discussed in this category

Do you typically see peripheral neuropathy in patients with castleman syndrome?

2 Answers available

For patients with newly diagnosed brain metastases without a history of seizure activity, do you routinely start anti-seizure medication?

If so, how long do you continue medication and when do you discontinue? Does treatment with surgical resection versus radiation alone change your man...

1 Answer available

What are some alternatives to dexamethasone for brain edema in patients who are allergic, have an intolerance, or refuse the medication?

5 Answers available

What would your next line treatment be for a patient previously treated with repeat resection, craniospinal irradiation, and initial cisplatin/vincristine/CCNU with medulloblastoma?

What would be your next treatment for a young adult patient with medulloblastoma refractory to repeat resection, craniospinal irradiation, and initial...

1 Answer available

Do you recommend continuous antibiotic prophylaxis for patients on complement inhibitors such as eculizumab?

Do you just use antibiotic prophylaxis if therapy is started prior to meningococcal vaccination?

3 Answers available

How do you manage AEDs in patients with malignant brain tumors?

Do you ever add prophylactic Keppra (levetiracetam) for glioblastoma patients without a seizure history based on data such as this study (nature.com) ...

5 Answers available

How do you manage drug-induced thrombocytopenia when the implicated drug is essential?

e.g. DITP from eptifibatide after a cardiac intervention

1 Answer available

What features help distinguish thyroid myopathy from immune checkpoint inhibitor-associated myopathy?

1 Answer available

How do you approach treatment of a glioblastoma in pregnancy?

3 Answers available

Is placing a VP shunt a major risk to spread medulloblastoma or other malignant brain tumors into the gut?

1 Answer available

Papers discussed in this category

Pediatric emergency care, 2008-04

Clinical diagnosis of ventriculoperitoneal shunt failure among children with hydrocephalus.

Clin Nucl Med,

Extracranial Metastases From Glioblastoma With Primitive Neuronal Components on FDG PET/CT.

World J Surg Oncol, 2019 Mar 27

Clinical outcome of cerebrospinal fluid shunts in patients with leptomeningeal carcinomatosis.

Asian J Neurosurg,

Widespread Intra-abdominal Carcinomatosis from a Rhabdoid Meningioma after Placement of a Ventriculoperitoneal Shunt: A Case Report and Review of the Literature.

J. Clin. Oncol., 2020 Feb 14

Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001.

Cancer, 2020 May 19

Second cancer risk after primary cancer treatment with three-dimensional conformal, intensity-modulated, or proton beam radiation therapy.

Acta Neurochir (Wien), 2019 Jan 29

Influence of pregnancy on glioma patients.

Arthritis Rheumatol, 2021 Apr 01

Inflammatory Myositis in Cancer Patients Receiving Immune Checkpoint Inhibitors.

Cancer, 2011 Feb 01

Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors: a prospective, randomized, placebo-controlled, double-blind pilot trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-03-01

Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma.

Sci Rep, 2020 Jul 01

Association between survival and levetiracetam use in glioblastoma patients treated with temozolomide chemoradiotherapy.

Neuro Oncol,

SNO and EANO practice guideline update: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors.

Clin Microbiol Infect, 2018 Feb 07

ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Introduction).

Pediatr Blood Cancer, 2021 Apr 12

Temozolomide with irinotecan versus temozolomide, irinotecan plus bevacizumab for recurrent medulloblastoma of childhood: Report of a COG randomized Phase II screening trial.

Journal of neurosurgery, 2013-04

A prospective randomized trial of perioperative seizure prophylaxis in patients with intraparenchymal brain tumors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019-05-01

Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines.

Cochrane Database Syst Rev, 2020 Apr 28

Antiepileptic drugs as prophylaxis for postcraniotomy seizures.

Pediatr Blood Cancer, 2021 Oct

Idiopathic multicentric Castleman disease with TAFRO clinical subtype responsive to IL-6/JAK inhibition: A pediatric case series.

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