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Pain Medicine   

Questions discussed in this category

How do you counsel patients who want to understand why sublingual cyclobenzaprine works to relieve their fibromyalgia pain and other related symptoms?
3 Answers available
What do you recommend to patients when they are having an acute flare of fibromyalgia symptoms?
3 Answers available
Where in your treatment approach to fibromyalgia will you recommend sublingual cyclobenzaprine? 
Will you recommend this as a first-line agent? Will you use this as monotherapy or only in combination with other agents like duloxetine?
3 Answers available
How do you approach patients with fibromyalgia who are reluctant to consider a psychiatric component to their illness but present with clear mood or anxiety symptoms?
4 Answers available
Do you view the difference between oral and sublingual cyclobenzaprine as clinically significant? 
Will you try the sublingual formulation in a patient who has failed the oral formulation, or vice versa?
3 Answers available
How do you work with patients to establish reasonable treatment goals for the management of fibromyalgia-related pain?
What tools do you track to assess progress toward these goals?
2 Answers available
What is your approach to titration of sublingual cyclobenzaprine in your patients with fibromyalgia?
3 Answers available
How do you counsel patients who are interested in using kratom for chronic pain management?
4 Answers available
When would you consider testing for LGI1 antibodies in patients with unexplained neuropathic pain?
1 Answer available
Do you recommend neuromodulation treatments with an implantable device for patients with chronic painful diabetic neuropathy who have not responded to common oral therapies such as Gabapentin and Amitriptyline?
1 Answer available
What is the effectiveness of transmagnetic stimulation for patients with chronic pain, including chronic headaches?
3 Answers available
Do you use naltrexone in your patients with fibromyalgia?
 What are common drug interactions/things to be aware of?
2 Answers available
How do you navigate C-2 refills in patients who are stable in their treatment and do not otherwise need to be clinically seen monthly?
Would you consider charging a small fee for managing C-2 prescriptions between appointments instead of requiring the patient to come monthly?
7 Answers available


Papers discussed in this category

JAMA neurology, 2021 Jun 01
Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy: A Randomized Clinical Trial.
The Lancet. Rheumatology, 2023 Dec 05
Naltrexone 6 mg once daily versus placebo in women with fibromyalgia: a randomised, double-blind, placebo-controlled trial.
Pain reports, 2023 Jun 15
Low-dose naltrexone for treatment of pain in patients with fibromyalgia: a randomized, double-blind, placebo-controlled, crossover study.
The Lancet. Rheumatology, 2023 Dec 05
Is low-dose naltrexone for fibromyalgia another treatment disappointment?
Frontiers in medicine, 2023 Apr 25
High overlap in patients diagnosed with hypermobile Ehlers-Danlos syndrome or hypermobile spectrum disorders with fibromyalgia and 40 self-reported symptoms and comorbidities.
Frontiers in neurology, 2022 Nov 24
Efficacy of repetitive transcranial magnetic stimulation on chronic migraine: A meta-analysis.
American journal of physical medicine & rehabilitation, 2022 Jan 18
Effectiveness of High-Frequency Repetitive Transcranial Magnetic Stimulation in Migraine: A Systematic Review and Meta-analysis.
Current pain and headache reports, 2024 Jan 26
Utility of Repetitive Transcranial Magnetic Stimulation for Chronic Daily Headache Prophylaxis: A Systematic Review and Meta-Analysis.
The Lancet. Neurology, 2010-04
Single-pulse transcranial magnetic stimulation for acute treatment of migraine with aura: a randomised, double-blind, parallel-group, sham-controlled trial.
Cephalalgia : an international journal of headache, 2018-05
A multicenter, prospective, single arm, open label, observational study of sTMS for migraine prevention (ESPOUSE Study).
Headache, 2018-05
Transcranial Magnetic Stimulation for Migraine Prevention in Adolescents: A Pilot Open-Label Study.
Annals of neurology, 2021 Aug 30
Leucine-Rich Glioma-Inactivated 1 versus Contactin-Associated Protein-like 2 Antibody Neuropathic Pain: Clinical and Biological Comparisons.
Arthritis and rheumatism, 1994-01
Comparison of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia. A randomized, double-blind clinical trial.
Pain medicine (Malden, Mass.), 2025 Jul 08
Pain Relief by Targeting Nonrestorative Sleep in Fibromyalgia: A Phase 3 Randomized Trial of Bedtime Sublingual Cyclobenzaprine.
Arthritis care & research, 2023 Jul 04
Efficacy and Safety of Sublingual Cyclobenzaprine for the Treatment of Fibromyalgia: Results From a Randomized, Double-Blind, Placebo-Controlled Trial.
Annals of medicine, 2011 Jul 19
Fibromyalgia diagnosis and diagnostic criteria.

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