Do you hold ADT before work up for prostate cancer when ordering advanced imaging such as PSMA PET?

The answer to this question is somewhat context dependent. The influence of ADT on a PSMA PET/CT is likely dependent on the clinical setting in which PSMA imaging is being considered, the duration of ADT prior to imaging, and how a provider plans to use the information to influence his or her treatm...

It is important to evaluate both castration-sensitive and castration-resistant models and patients, short and long term ADT with various agents (e.g., short term ADT use of orchiectomy vs LHRH agonist minus plus antiandrogen vs LHRH antagonist) and methods of action, as well as initial and late resp...