Do you hold ADT before work up for prostate cancer when ordering advanced imaging such as PSMA PET?

Topics: Radiation Oncology • Genitourinary Cancers • Prostate Cancer • Medical Oncology

Do you worry about false negatives on PET, CT, MRI if ADT is started before the scan? Scheduling scans can sometimes book 2-4 weeks out.

Answer from: Radiation Oncologist at Academic Institution

The answer to this question is somewhat context dependent. The influence of ADT on a PSMA PET/CT is likely dependent on the clinical setting in which PSMA imaging is being considered, the duration of ADT prior to imaging, and how a provider plans to use the information to influence his or her treatm...

Comments

Radiation Oncologist at University of Florida
Yes, if feasible.

Radiation Oncologist at Lafayette Radiation Center
I've done 10 Ga-PSMA and 4 Pylarify past year. Goi...

Answer from: Medical Oncologist at Community Practice

It is important to evaluate both castration-sensitive and castration-resistant models and patients, short and long term ADT with various agents (e.g., short term ADT use of orchiectomy vs LHRH agonist minus plus antiandrogen vs LHRH antagonist) and methods of action, as well as initial and late resp...

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