Do you offer whole lung radiation with metastatic recurrence of Wilm's Tumor (FH, no LOH 1p16q)?

Topics: Radiation Oncology • Pediatric Oncology

What is the timing and role of surgery and RT at salvage for a lung recurrence?

Patient initially presented with lung metastases, but achieved CR with chemotherapy and thus whole lung irradiation was omitted up front per AREN0533.

Answer from: Radiation Oncologist at Academic Institution

WLI should certainly be administered alongside salvage chemotherapy for metastatic recurrence. There are no definitive data on timing, but the earlier the better.See the relapse arm of NWTS-5 (Malogolowkin et al., PMID 17539021, Green et al., PMID 16547940) and AREN1921...

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Radiation Oncologist at Washington University School of Medicine
The age of the patient is not stated, which is imp...

Radiation Oncologist at NYU Langone Medical Center
The patient is 3 years old, initially presented wi...

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