Do you offer whole lung radiation with metastatic recurrence of Wilm's Tumor (FH, no LOH 1p16q)?
What is the timing and role of surgery and RT at salvage for a lung recurrence?
Patient initially presented with lung metastases, but achieved CR with chemotherapy and thus whole lung irradiation was omitted up front per AREN0533.
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Northwestern University Feinberg School of Medicine
Answered on
WLI should certainly be administered alongside salvage chemotherapy for metastatic recurrence. There are no definitive data on timing, but the earlier the better.
See the relapse arm of NWTS-5 (Malogolowkin et al., PMID 17539021, Green et al., PMID 16547940) and AREN1921 for details regarding integra...
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