Do you recommend a specific XRT fractionation for young men with prostate cancer?
Given younger men have a longer period to live, are there concerns regarding long term side effects (GI, GU, secondary malignancy) between SBRT vs hypofractionation vs standard fractionation?
1 Answer
Mednet Member
Radiation Oncology · Karmanos Cancer Institute - McLaren Proton Therapy Center
Answered on
I don't think I would use a different curative dose or fields, but I would use protons. Greater longevity, like 40+ years, increases the risk of 2nd malignancy. The integral dose with protons is about two-thirds less than with Xrays, and the secondary malignancy rate reflects that. The risk is only ...
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