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Does an EGFR mutation in a never-smoker change your radiation treatment recommendations for ES-SCLC?

1 Answer
Mednet Member
Mednet Member
Radiation Oncology · Tennessee Oncology
Answered on

First, worth a close pathology review at a specialty center. EGFR mutations in de novo small cell are exquisitely rare. The more common scenario is small cell transformation from adenocarcinoma. If this has features of adenocarcinoma, I’d favor a metastatic non small cell paradigm with EGFR inhibiti...

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