Does the use of slow release hormone replacement therapy impact your adjuvant treatment recommendations for a perimenopausal patient with an intermediate Oncotype score?

If she had a testosterone pellet this would not sway me to give chemo in someone who would otherwise get endocrine therapy alone. I would give the AI and monitor estradiol levels as the pellet wears off. Small studies of testosterone + anastrozole pellets didn't detect increased estradiol levels whe...