For a metastatic neuroendocrine tumor patient who has experienced prolonged progression free survival, how would you approach surgical debulking?

This is a complicated answer (especially for me as a medical oncologist...). The main factors to consider are the tumor grade, tumor behavior, extent and location of metastases, patient's age and performance, and the location of the primary tumor.

For a patient with a G1/G2 pancreatic or SB NET with...