For esophageal adenocarcinoma with extensive associated Barrett's, would you extend your CTV coverage beyond the usual expansions to cover the areas of known Barrett's?

The standard GTV to CTV expansions may include much of the Barrett's, but I would not deliberately target the Barrett's disease, whether treating with neoadjuvant or definitive intent. Chemoradiation is not a proven therapy for Barrett's disease, but treating a larger field will expose more heart an...