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For locally advanced NSCLC with additional synchronous NSCLC primaries in the same lung or lobe, what is your approach to definitive therapy?

E.g. One NSCLC with N2 disease, and additional ipsilateral small nodule that is a biopsy-proven second primary. When do you consider SBRT to a nodule vs incorporating all into the chemoradiation fields?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Yale School of Medicine
Answered on

This is a situation that comes up surprisingly frequently and can be challenging to navigate. This assumes that one is certain which of the two lung lesions is the primary (i.e. based on discordant pathology or genomic profiling results of the nodal metastasis and/or first primary compared to the se...

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