For patients with ovarian cancer, do you order folate receptor-alpha testing at initial diagnosis, first recurrence, or first instance of platinum resistance?

I usually order at initial diagnosis because:

1. We have tumor specimen to test on at the initial dx
2. Most advanced ovarian cancer will recur initially as platinum-sensitive. But eventually, most of the patients will become platinum-resistant
3. I have not seen convincing data that folate receptor changes...

I’ve been moving testing overall to more comprehensive assessment (NGS and expression) and earlier as a general practice. I do this because clinical trials are expanding both in scope and line of therapy and I want to have this information to be able to have a more comprehensive discussion with my p...

I had been ordering testing at the time of recurrence however, with delays I find that in my clinic, ordering testing at the time of diagnosis provides myself and the patient the best opportunity to plan out their care both at diagnosis and recurrence. For stage I tumors, I do not order at diagnosis...