Given the recent pooled analysis of STARS and ROSEL trials, can we say SBRT for early stage NSCLC is equivalent to lobectomy based on level 1 evidence?
Will the NCCN guidelines change based on this study?
Answer from: Radiation Oncologist at Community Practice
We still do not have Level I evidence to answer such a question. Both STARS and ROSEL closed prematurely. If we read @Joe Y. Chang's Lancet Oncology paper more carefully, unlike others who have interpreted it as radiation oncologists running amock to claim SBRT is now equivalent to surgery, the disu...
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Answer from: Radiation Oncologist at Academic Institution
It is still too early to state that SBRT should replace lobectomy as a standard treatment for operable stage I NSCLC due to small case number in this randomized study. However, SBRT should be considered as a treatment option for operable stage I NSCLC. We will continue to push NCCN guidelines as mo...