Have you seen drug induced SCLE from IL-17 inhibitors?

Topics: Rheumatology • IL-17 Inhibitors • Systemic lupus erythematosus • General Rheumatology • Dermatology • Cutaneous lupus

And if so, what is your approach to the diagnosis?

Answer from: at Community Practice

Fortunately, drug-induced subacute cutaneous lupus erythematosus (diSCLE) induced by IL-17 inhibitors is rare. I have never seen a case, but there are at least 3-4 cases in the medical literature (from brodalumab, ustekinumab, and secukinumab: Ang et al., PMID 33511692, Tierney et al., PMID 30891478...

Comments

at Medstar
Thank you so much!! So helpful.

at Affliated Dermatologist Inc.
Very helpful! I realize ustekinumab has a downstre...

at Uniformed Services University of the Health Sciences (USUHS)
@Edward Searle: You are absolutely correct. Thanks...

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