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How do you decide until what age to offer ovarian preservation for patients with biopsy-proven grade 1 or grade 2 endometrial cancer without evidence of metastatic disease on imaging or at the time of surgery?

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Under what age do you typically recommend ovarian preservation in women with low-grade, suspected early-stage endometrial cancer?

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2 Answers
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Gynecologic Oncology · BayCare Medical Group
Answered on

I often reference Jason Wright's article evaluating the safety of ovarian preservation up to age 45 regarding cancer-related mortality. Granted, this doesn't measure recurrence rates. I also reference Dr. Barakat's incomplete GOG study (a casualty of the WHI study) that found only ~2-3% of patients ...

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Gynecologic Oncology · Center of Hope
Answered on

Ovarian Conservation in patients with biopsy-proven grade 1 or grade 2 endometrial cancer (no evidence of metastatic disease on imaging or at time of surgery)?

There is increasing evidence suggesting ovarian function confers health benefits until at least the age of menopause. In premenopausal patien...

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