How do you manage obsessive-compulsive symptoms secondary to clozapine?  

You have to find a good balance, which can be very challenging if the psychosis and OCD are prominent. Clozapine exacerbates OCD the most out of any antipsychotic. You can use Luvox to help boost clozapine levels and decrease norclozapine levels, which is the main culprit of metabolic side effects; ...