How do you treat endometrial cancer in the setting of a pCR after neoadjuvant chemotherapy?  

Female in her 60s who had presented originally with well-differentiated endometrioid adeno clinically and radiographically involving bilateral parametria. She was felt to not be a surgical candidate upfront, and thus received 3-4 cycles chemotherapy. TAH/BSO showed no residual carcinoma. Would you recommend treatment based on initial stage? If so, would you recommend EBRT or brachytherapy?



Answer from: Radiation Oncologist at Community Practice