How does the updated classification system of gliomas impact your recommendations for radiation?

Minesh Mehta and @Dr. First Last, Miami Cancer Institute

In 2021, the World Health Organization (WHO) introduced significant new changes to the classification of tumors of the central nervous system (CNS) in their 5^th edition (WHO CNS5) (Louis et al., PMID 34185076). This step was the first of many ...

The issue of IDH wild type malignant glioma without TERT promoter mutations remains one of the vexing issues with the current classification. It is estimated that perhaps about 20% of GBMs lack genetic alterations in IDH (hence IDH wild-type) and also the TERT promoter (hence TERTp wild-type). An in...

ASTRO guidelines just published https://www.practicalradonc.org/article/S1879-8500(22)00144-8/fulltext#relatedArticles.