How would you approach adjuvant therapy for a patient with pT2N2 lung adenocarcinoma who underwent an R1 resection and is not amenable to further surgical intervention?

Topics: Lung Cancer • Radiation Oncology • Thoracic Malignancies • Medical Oncology • NCI-CCC Tumor Board Question • University of Michigan • NCI-CCC Thoracic Tumor Board Question

NGS without any actionable mutations and PD-L1 TPS 15%.

Would you offer chemotherapy, radiation, or immunotherapy and, if so, in what order?

Answer from: Medical Oncologist at Academic Institution

I don't know that I have a trial (much less a randomized one) to prove this, however in this situation, assuming the patient has adequate functional status and has recovered sufficiently from surgery, I would treat the surgery as an extended biopsy. I.e., I would probably (with my radiation colleagu...

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Radiation Oncologist at Quillen VA Medical Center
The treatment for N2 + post op is chemo du jour by...

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