Topics:
Radiation Oncology • Gynecologic Cancers
How would you manage an endometrial cancer with no (or minimal) myometrial invasion and only a very small focus of disease in a pelvic node?
Would you still consider this high risk? If so, would you recommend pelvic radiation AND chemotherapy?
Answer from: Radiation Oncologist at Community Practice
Eventhough stage IIIC endometrial cancer is the most common sub-stage among locally advanced patients, patients with node positive disease have routinely been combined with other stages for clinical trial purposes (including high risk early stage disease, stage IV, and recurrent disease). This not ...
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Answer from: Radiation Oncologist at Academic Institution
Generally patients who have no invasion of the myometrium do not develop lymph node metastases (although we have seen rare exceptions); for patients who have inner half invasion, the risk is related to grade, the actual depth of invasion and other factors---small high-grade tumors without LVSI rarel...