How would you manage RT for a locally advanced squamous cell carcinoma of the anal canal in a >90-year old if chemotherapy is not recommended?

For any elderly patient, a discussion of goals of care in the context of symptoms is warranted. In the chance this is a small asymptomatic cancer in a patient with limited life expectancy, no therapy may be reasonable. However, this does not seem to be the case for your patient.

If the patient is dee...

RT alone.