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How would you manage treatment of a cervical cancer in a patient unable to tolerate chemotherapy or an HDR boost due to medical commodities?

Would you utilize IMRT to provide a boost to gross disease? If so, how would you define your treatment volumes and what dose would try to achieve? Also, what dose-fractionation would you favor for the initial whole pelvis fields (4500 cGy in 25 fractions versus 5040 cGy in 28 fractions)?
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Radiation Oncology · University of Texas MD Anderson Cancer Center
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The first step is to be absolutely certain that brachytherapy is not feasible. In our experience this is extremely rare. The patient should have a thorough medical evaluation and have their medical conditions optimized as much as possible before the decision is made to withhold these standard elemen...

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Radiation Oncology · Loyola University Chicago Stritch School of Medicine
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I would reiterate what Dr, Eifel stated – it should be extremely rare not to be able to provide brachytherapy. In 24 years of treating cervical cancer, I have never not delivered brachytherapy for a medical comorbidity.

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Radiation Oncology · University of Kentucky
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I would emphasize one other point made in @Dr. First Last's response. We cured many patients with cervical cancer using RT alone, before concurrent chemotherapy became standard. If a patient cannot receive or doesn't accept chemotherapy as part of the treatment, cure is still possible, even likely, ...

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