In staging Hodgkin's lymphoma, would you identify a PET+ bony focus as disease when there are no associated bone changes on CT and a biopsy was not obtained?

The staging bone marrow biopsy was negative. The staging manual simply states "bone involvement is identified using appropriate imaging studies." Is PET+ alone sufficient? Would location of site relative to nodal disease and/or extent of nodal disease change your assessment? If a biopsy of the site was NOT obtained pre-chemo and the restaging scan after initial chemo shows resolution of the bony hypermetabolic activity, would you irradiate the site as part of consolidative therapy?