Retrospective data suggest pelvic RT helps but the volume of pelvic RT is variable as much of the data is in the 2D era. I usually treat common, external, and internal iliac in recurrent disease but would be reasonable to exclude common illiac node if morbidity is a concern.Vargo et al., PMID 252419...

In general, I agree with Dr. @Beriwal's answer. However, a case presented here is a very favorable recurrence disease. She had low-risk endometrial cancer before surgery and also a very small mucosal recurrence. I do not have data to support and experience but I wonder if small pelvic RT with HDR br...

I can't think of a specific case that I would consider treating low-pelvis (meaning not treating common iliac nodes to the level of the aortic bifurcation) for a vaginal recurrence of endometrial cancer. Perhaps someone with a significant history of IBD or other reasons to warrant toxicity concerns...