Is there a role for extended treatment volumes (elective nodal) in the definitive treatment of parameningeal rhabdomyosarcoma in a young adult?
Would the translocation status influence your decision? Are there specific subsites where elective radiotherapy likely offers a higher therapeutic ratio? Would retropharyngeal nodal involvement modify your decision? Is there a role for sentinel lymph node evaluation prior to chemotherapy?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Washington University School of Medicine
Answered on
If by "extended treatment volumes" you are asking about cranial or craniospinal radiation therapy, the answer is an emphatic NO. We demonstrated by careful review of patterns of failure that cranial irradiation was unnecessary in PM-RMS (Michalski 2004). The IRS and subsequently the COG have abandon...
Join for free or sign in to see the full answer