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What dose and expansion of GTV is recommended for a low grade glioma?

In a large unresectable grade 2 astrocytoma of the temporal lobe, what dose and GTV margin should be used?
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What is your preferred dose/fractionation for low-grade glioma?

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1 Answer
Mednet Member
Mednet Member
Radiation Oncology · Quint Cities Radiation Oncology
Answered on

I think doses between 45-54 Gy are probably reasonable for low grade gliomas when electing to treat with RT. Several studies have not shown a benefit with dose escalation in the treatment of low grade gliomas (EORTC 45 Gy vs 59.4 Gy; Intergroup 50.4 Gy vs 64.8 Gy).

In terms of treatment volumes, RTO...

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