What dose constraint do you use for the spinal cord in the setting of re-irradiation?
What factors do you consider when determining this constraint? For example, in a patient who was previously treated to 30 Gy in 10 fractions, how would you determine spinal cord tolerance in the setting of SBRT?
2 Answers
Mednet MemberInvited Expert
Radiation Oncology · University of Washington School of Medicine
Answered on
Dr. Arjun Sahgal published the dose constraints in Red J.
Reirradiation human spinal cord tolerance for stereotactic body radiotherapy.
Sahgal A, Ma L, Weinberg V, Gibbs IC, Chao S, Chang UK, Werner-Wasik M, Angelov L, Chang EL, Sohn MJ, Soltys SG, Létourneau D, Ryu S, Gerszten PC, Fowler J, Wong CS, Larson DA. Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):107-16. doi: 10.1016/j.ijrobp.2010.08.021. Epub 2010 Oct 15. PMID: 20951503
Mednet MemberInvited Expert
Radiation Oncology · University of Washington School of Medicine
Answered on
The timing, contribution dose from SBRT, and total nominal BED (2 Gy eq) were discussed.