What is an acceptable upper limit for ipsilateral lung V8 Gy when using the FAST-Forward regimen with high tangents to cover limited axillary disease?
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3 AnswersMednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network
I would say ipsilateral V8 is more for the ALARA principle and not based on risk of Pneumonitis, and thus would accept a higher number to cover low axillary if needed.
Mednet Member
Radiation Oncology · Emory University Hospital
The UK FAST-Forward nodal sub-study (covering axillary levels I-IV without IMN coverage) permitted an ipsilateral lung V30% of up to 25% and reported comparable rates of symptomatic lung fibrosis (2%) at 5 years for both the 40 Gy/15 Fx and 26 Gy/5 Fx schedules (Brunt et al., PMID 40379410).