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What is the radiation volume for unresected gross paraaortic lymph node in a Wilms patient?

Do you radiate the paraaortic chain to 10.8Gy then boost gross residual with 1cm block edge margin to 19.8Gy or simply treat the entire paraaortic chain to 19.8Gy w/o cone down? Why is unresected gross node dose 19.8Gy but unresected gross disease dose 21.6Gy?
1 Answer
Mednet Member
Mednet Member
Radiation Oncology · St Jude Children's Research Hospital
Answered on · Updated on

This depends on the presence/absence of diffuse anaplasia (See AREN0321 [NCT00335556]) and age/field extent.

Patients with diffuse anaplasia who are Stage 3 due to the presence of residual nodal disease would receive 19.8 Gy to the flank, and then in the presence of residual disease, would receive a ...

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