What is the role of preoperative radiation in patients with bone metastases needing surgical stabilization (ie. ORIF), but without tumor resection?  

If a patient has a large femoral metastasis that cannot be resected, but is to be stabilized with ORIF which will push tumor into the distal end of the rod, can pre-op radiation obviate the risk of tumor spread and reduce the chance or recurrence?

What would be an appropriate dose, fractionation, and volume for treatment in such a case?



Answer from: Radiation Oncologist at Academic Institution