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What is the role of upfront pembrolizumab in metastatic PD-L1 positive NSCLC presenting with SVC syndrome?   

Would starting with chemotherapy be preferred in this situation and consider concurrent radiation, then switch over to Pembrolizumab once some control is achieved?



Answer from: Medical Oncologist at Academic Institution
Comments
Medical Oncologist at Einstein Medical Center Philadelphia
Thank you @Balazs Halmos and @Nitin Ohri, ver...
Medical Oncologist at UNC/Rex Healthcare
Thank you both! Great Discussion!!
Medical Oncologist at Dayton Physicians Network Hematology
Thank you Dr Halmos and Dr Ohri for such an excell...
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