Would you recommend PMRT in a patient with a microinvasive component but a large DCIS component who had a mastectomy with negative margins?

Patients with DCIS treated with mastectomy and negative margins wouldn't get PMRT, so this patient wouldn't either. Essentially, they have an extensive intraductal component, and EIC with negative margins is not a risk for recurrence, thus PMRT would not be warranted.