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Endocrinology

Pediatric Hematology/Oncology   

Questions discussed in this category

How would you counsel a female to male transgender patient regarding VTE risk with testosterone therapy, who has additional mild-moderate risk factors for thrombosis?
Additional risk factors could be family history of VTE or thrombophilia, such as antithrombin deficiency.
1 Answer available
How do you approach a young patient with metastatic poorly differentiated thyroid cancer with rhabdoid/non-anaplastic features?
2 Answers available
How do you monitor risk of erythrocytosis from testosterone use for female to male transgender patients?
1 Answer available
How do you counsel cancer patients when they ask if they should avoid sugar?
9 Answers available
In a young female with severe osteoporosis due to congenital estrogen deficiency, can estrogen be prescribed if genetic testing for congenital disorders reveals a heterozygous Factor V Leiden mutation?
No prior thrombosis; no family history of thrombosis. As per endocrine, the only useful therapy for the osteoporosis is estrogen. 
1 Answer available
Are there contraindications to growth hormone therapy in patients who have completed treatment for pediatric cancer?
1 Answer available
When treating patients with immune checkpoint inhibitors, do you routinely check markers of endocrinopathies such as TSH/ACTH, or only when a patient has symptoms?
If so, how often do you check these labs?
1 Answer available
What recommendations do you have for a transgender female patient with history of prothrombin gene mutation who is interested in starting gender affirming hormone therapy?
The patient has no personal history of VTE, but has positive family history of VTE.  Any prophylactic anticoagulation options? How would manage...
1 Answer available
How do you incorporate denosumab into the surgical management of giant cell tumor of bone?
Does the degree of resectability affect your management?
2 Answers available
How do you counsel male-to-female transgender patients on the VTE risk of hormonal therapy?
1 Answer available


Papers discussed in this category

BMJ, 2008 May 20
Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis.
Circulation,
Hormone therapy and venous thromboembolism among postmenopausal women: impact of the route of estrogen administration and progestogens: the ESTHER study.
Endocrine reviews, 2019-02-01
Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update.
Eur J Endocrinol, 2022 Apr 21
Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement.
Pediatr Hematol Oncol, 2023 Mar 20
Growth hormone after CNS tumor diagnosis: the fundamentals, fears, facts, and future directions.
Clinics (Sao Paulo, Brazil), 2018 Dec 10
Autophagy and intermittent fasting: the connection for cancer therapy?
Metabolites, 2020 Jul 11
The Pentose Phosphate Pathway Dynamics in Cancer and Its Dependency on Intracellular pH.
Protein & cell, 2014 Jul 12
Regulation of the pentose phosphate pathway in cancer.
Trends in biochemical sciences, 2016 Jan 05
The Warburg Effect: How Does it Benefit Cancer Cells?
Journal of thrombosis and haemostasis : JTH, 2019 Sep 13
Transgender patients and the role of the coagulation clinician.
The Journal of clinical endocrinology and metabolism, 2024 Jan 18
Approach to the Patient: Hormonal Therapy in Transgender Adults With Complex Medical Histories.

Related Topics in Endocrinology

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