General Internal Medicine

Psychiatry   

Questions discussed in this category



Is there an absolute cutoff for AST/ALT that you use where the risks outweigh the potential harm reduction benefits of using the medication? &nbs...

How do you weigh cardiovascular risks against the potential functional and emotional consequences of undertreated ADHD? What blood pressure thresholds...

Related Q&A on antipsychotics in Alzheimer's.In light of the publication from Choma et al., PMID 41063545.

Are there any special concerns for antipsychotics with a higher anticholinergic burden?

For your recommended medication, are you doing a scheduled set dose, or is it primarily symptom-driven? 

Do you use different approaches in different settings (i.e., the ED vs. outpatient clinic)? Do you use different approaches for chronic vs acute suici...

How do you approach shared decision-making when patients express hesitancy about medication exposure in utero? What is your approach when a patient is...

In what patient populations would you consider using disulfiram (Antabuse) instead of, or in addition to, acamprosate or naltrexone? In your experienc...

How do you educate patients about the role exercise may play in depression treatment? What type, frequency, and intensity of exercise do you recommend...

How do you critically assess the evidence base for functional medicine approaches? How do you respond when patients specifically request functional me...

Assume QTc is not prolonged, electrolytes are reasonably normal, and the patient is not already on heavy psychotropic polypharmacy.

Do you avoid certain antidepressants related to the risks on suppressing respiratory-drive which is potentially concerning in patients with high cord ...

Would you consider the risk of masking autonomic signs of alcohol withdrawal with clonidine different from beta-blockers?

Which genetic/other testing should be considered in an early-onset dementia work-up? 

Should one restart lamotrigine or look for an alternative? If no other alternative available, is slow titration vs regular titration preferred?


Papers discussed in this category


JAMA network open, 2022 Dec 01

International journal of antimicrobial agents, 2023 Jun 08

Pharmacy (Basel, Switzerland), 2023 Nov 20

International journal of antimicrobial agents, 2023 May 07

J Acad Consult Liaison Psychiatry, 2023 Nov-Dec

Case reports in nephrology and dialysis, 2021 Aug 04

The primary care companion for CNS disorders, 2022 Dec 08

Transplantation direct, 2023 Jul 12

Alcohol (Fayetteville, N.Y.), 2014-06

Neurology, 1991 Mar

Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2013 Aug 31

The European respiratory journal, 2020 Apr 21

Journal of sleep research, 2023 Jul 05

Expert opinion on pharmacotherapy, 2023 Jun 27

The American journal of psychiatry, 2010-06

Depression and anxiety, 2013-06

Journal of addiction medicine, 2021 May-Jun 01

The American journal on addictions, 2023 Mar 20

Drug and alcohol dependence, 2024 Sep 07

JAMA psychiatry, 2025 Apr 01

Journal of addiction medicine, 2020 May/Jun

American journal of preventive medicine, 2015-10

JHEP reports : innovation in hepatology, 2024 Apr 10

The Cochrane database of systematic reviews, 2006-07-19

Psychiatry and clinical neurosciences, 2010 Feb 01

Basic & clinical pharmacology & toxicology, 2023 Jun 20

Ochsner journal, 2013 Winter

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013-06

Case reports in cardiology, 2016

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG, 2016 May-Jun

Headache, 2005 Feb

Neurology, 2004 May 25

The Cochrane database of systematic reviews, 2014-03-21

Translational psychiatry, 2022 Apr 01

Journal of sleep research, 2020 Dec 02

Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2016 Jan 27

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022 Dec 01

CNS drugs, 2024 Aug 09

PM & R : the journal of injury, function, and rehabilitation, 2022 Jan 12