Questions discussed in this category
When using hypofractionated RT (i.e., 67.5 Gy in 15 fractions), can chemotherapy be delivered concurrently?
Options for systemic therapy in NCC...
If so, what regimen? At what point is it safe to start chemo in a freshly transplanted liver?
And is there any role in utilizing FGFR2 inhibitors in first line setting?
The PROOF trial utilizing Infigratinib in first line was stopped after the...
Would you offer single agent immunotherapy or chemo-immunotherapy with gem/cis durva/pembro?
Is liquid biopsy helpful? Would you treat if this shows somatic mutation?
4 months of Neoadjuvant GAP resulted in conversion from unresectable to resectable.
If the patient had PSC and baseline atrophy preventing brachytherapy boost (received SBRT boost instead), would this change your threshold for stentin...
If so, what assay would you use in this population?
Do we have data on TMB/PDL1 status of long-term survivors?
TOPAZ-1 trial allowed for up to 8 cycles of gem/cis. Were there differences in chemotherapy duration/# cycles between treatment groups? Does use of du...
How would you balance the OS benefit from TOPAZ-1 with the risks of immunotherapy in this or other high-risk populations?
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Papers discussed in this category
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-08-20
Lancet Oncol., 2019 Mar 25
NEJM Evidence, 2022 Jun 1
Advances in radiation oncology, 2016
Gastroenterology, 2012-07
Brachytherapy, 2018
Cancer, 2005-01-01
Cancer chemotherapy and pharmacology, 2011-12
JAMA oncology, 2018-12-01
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010 Sep 20
British journal of cancer, 2008 Sep 16
Cancer chemotherapy and pharmacology, 2009 Jan 14
Cancer, 2007 Sep 15
Annals of oncology : official journal of the European Society for Medical Oncology, 2013 Aug 23
Gastrointestinal endoscopy, 2012-01
Gastrointestinal endoscopy, 2012 Feb
N Engl J Med,
JAMA oncology, 2021 Jun 01
Journal of gastrointestinal oncology, 2020 Aug
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-01-20
N. Engl. J. Med.,
Pract Radiat Oncol, 2021 Oct 21
Lancet (London, England), 2023 Apr 16
NEJM evidence, 2022 Jun 01