Medical Oncology

Palliation   

Questions discussed in this category


From NCCN (Rectal MS-33): SBRT is a reasonable option for patients who cannot be resected or ablated. What is the role of SBRT versus microwave ablat...

How do you counsel patients and caregivers? Do you prescribe medications (''appetite stimulants'') with the goal to improve appetite even if they do n...

This has become standard practice at our institution for patients with a good performance status, with whole brain radiotherapy given after the comple...

Notably, the patient presented with renal failure due to ureteral obstruction and hydronephrosis, receives hemodialysis, and has limited systemic opti...

A recent NCBD analysis (Rusthoven et al., PMID 27325855) suggests that the addition of prostate RT significantly improves survival compared to AD...

There was a recall on viscous lidocaine and many of our patients cannot find it. What would you recommend as alternatives?

How do you "have the talk" in a way that is straightforward without emotionally crushing the patient?

Is radiation effective in this case and if so, what dose would you use? Is there potential for perforation?

Are you offering patients beta-emitters (Samarium-153 lexidronam, strontium-89) to any patients?

Based on the SCORAD III trial, will you now be treating patients with spinal cord compression with single-fraction radiotherapy? Is there anyone ...

Do you prefer WBRT, IT chemo or targeted systemic therapy and what is your preference on the sequence of therapies?

If a patient has a large femoral metastasis that cannot be resected, but is to be stabilized with ORIF which will push tumor into the distal end of th...

There are many delivery methods of cannabis, including smoking, ingesting it through food, or inhaling it. Is one method more effective than another?

How do you decide between supportive care v. chemoimmunotherapy? Is there a threshold of disease burden that would push you towards recommending hospi...

Obviously, patient and caregiver preferences are paramount. But, what factors do you consider? Does expanded hospice (e.g., Medicare Care Choices) inf...

Is there specific workup you perform? Are there preventive measures? Once established, are there non-pharmacological and pharmacological treatments yo...

Would you suspect progressive disease v. radiation necrosis vs optic neuritis due to immunotherapy. Eyes were within radiation field 8 months ago.&nbs...

Specifically, how do you explain potential cognitive decline in a way that explains what changes they can expect in their daily lives?

How about those with metastatic disease eager to maintain quality of life? Do you risk progression of disease if the TNF blocker is re-started?

Is this recommended in a certain subset of patients (EGFR positive or 1 metastasis only)? Or should we await maturation of the MD Anderson/Colorado/On...

Can SRS or whole brain radiotherapy be reserved for progression in these young, healthy patients?

Does your management differ if the hiccups are felt to be related to chemotherapy as opposed to the disease itself?

The immediate response by patients in this situation seems almost universally to be, "But I'll starve to death!" Referencing literature about lack of ...

Does the site of palliative radiation therapy matter (i.e. femur, abdomen, pelvis vs base of skull)? How long should you wait to give palliative ...

We have a great palliative care clinic and I like to refer many patients with metastatic disease, even if I feel that they will live a year or two lon...

If the systemic agent is going to be held, how many days prior to starting radiation therapy should the agent be held and when can it be restarted aft...

I know that some would argue that healthy patients with an excellent performance status may not need an early palliative care referral, but wouldn't i...

What factors should be considered with offering SBRT to oligometastatic bone disease in prostate cancer patients? Should this been done off of a proto...

My patient’s family has asked that I don’t tell her that she has metastatic cancer because it will devastate her. I am planning on palliat...

I've read about patients who were treated with concurrent bevacizumab-RT who developed lethal tracheoesophageal fistulas. How long would you have to w...


Papers discussed in this category


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JAMA,

International journal of radiation oncology, biology, physics, 2013-09-01

N Engl J Med, 2007 Aug 16

J Clin Oncol, 1999 Jul

Lancet, 2015 Jan 3

International journal of radiation oncology, biology, physics, 2011-11-01

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Lancet Oncol., 2017-05-01

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BMC Cancer, 2015-08-15

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Practical radiation oncology, 2015

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BMC Cancer, 2015-03-04

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The Lancet. Oncology, 2009-11

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007-04-01

J Clin Oncol, 2011 Jan 10

JAMA, 2016-07-26

Radiation oncology (London, England), 2014-09-30

Cancer, 2016-06-15

J. Clin. Oncol., 2018 May 22

Lung cancer (Amsterdam, Netherlands), 2018-06

The New England journal of medicine, 2018-08-23

The New England journal of medicine, 2018-12-06

International journal of radiation oncology, biology, physics, 2019-04-01

Lancet, 2019 Oct 04

JAMA oncology, 2019-06-01

International journal of radiation oncology, biology, physics, 2019-04-01

International journal of radiation oncology, biology, physics, 2019-04-01

Neurosurgery, 2019 Oct 10

JAMA Oncol, 2020 Jun 4

J Clin Oncol, 2020 Aug 10

Lung Cancer, 2014 Aug 02

N Engl J Med,

Lancet Oncol, 2020 Apr 03

Int J Radiat Oncol Biol Phys,

JAMA,

J Neurosurg,

Cancer,

The New England journal of medicine, 2010-08-19

The New England journal of medicine, 2013-03-28

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-05-01

International journal of radiation oncology, biology, physics, 2018-03-15

International journal of radiation oncology, biology, physics, 2016-06-01

Int. J. Radiat. Oncol. Biol. Phys.,

Radiat Oncol, 2015 May 27

International journal of radiation oncology, biology, physics, 2016-06-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-04-01

The New England journal of medicine, 2016-11-10

The New England journal of medicine, 2018-01-11

N. Engl. J. Med.,

Eur Urol, 2015 Jul 16

BJU Int, 2009 Feb

European urology, 2014-06

Anticancer Drugs, 2016-06-01

Practical radiation oncology, 2011

N Engl J Med, 2014 Mar 27

N Engl J Med, 2013 Jun 20

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-12-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008-04-01

Lancet Oncol., 2010-02-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-03-20

The Journal of urology, 2005-08

Mol Clin Oncol, 2015 May 04

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-12-10

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013-11-10

The Journal of urology, 1999-07

Annals of oncology : official journal of the European Society for Medical Oncology, 2009-03

Mayo Clin Proc, 2004 Oct

JNCI Cancer Spectr, 2019 Oct 21

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The New England journal of medicine, 2018-05-03

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002-08-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011-06-20

The Journal of urology, 2002-09

Clinical cancer research : an official journal of the American Association for Cancer Research, 2009-01-15

Nature, 2005-12-08

The New England journal of medicine, 2001-12-06

Lancet, 2001-09-22

Breast Cancer Res. Treat., 2010-02-01

The Journal of urology, 1982-06

Cancer research, 2000-04-15

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Oncol. Rep., 2015-12-01

Nat Commun, 2015-04-01

PLoS ONE, 2016-01-01

J. Urol., 2002-04-01

Lancet Oncol., 2015 Sep 09

European urology, 2018-02

Lancet, 2018 Oct 18

Can Fam Physician,

Cancer, 2010-05-01

Int. J. Cancer, 2016 Jun 30

Neuro-oncology, 2013-10

International journal of radiation oncology, biology, physics, 2017-05-01

The Lancet. Oncology, 2017-08

Neurology, 1989-06

Radiother Oncol, 2020 Jan

Expert Opin Drug Saf,

The Lancet. Oncology, 2016-07

J Thorac Oncol, 2019 Feb 16

Int. J. Radiat. Oncol. Biol. Phys., 2019 Aug 31

Lung Cancer, 2019 Jan 15

JAMA oncology, 2017-06-01

Neuro-oncology, 2019-02-23

Lung Cancer, 2020 Sep 10

The New England journal of medicine, 2016-07-14

Practical radiation oncology, 2021 Sep-Oct

Palliative medicine, 2022 Mar 31

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023 Mar 28

J Clin Oncol, 2020 Jul 13

Practical radiation oncology, 2015

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011-10

Journal of oncology practice, 2019-01

Support Care Cancer, 2021 Aug 16

The New England journal of medicine, 2013-07-18

N Engl J Med, 2021 Jun 23

Journal of palliative medicine, 2012-11

Nature reviews. Clinical oncology, 2016-03

JAMA, 2019 Apr 16

Head Neck, 2016 Mar 29

The Lancet. Oncology, 2017-05

BMC Cancer, 2014 Sep 15

JAMA Oncol,

JAMA oncology, 2023 Jun 01

Cancer, 2023 Jul 06

The Lancet. Oncology, 2023 Dec 08

Cardiovascular and interventional radiology, 2023 Jul 10