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Medical Oncology

KRAS   

Questions discussed in this category


How do you manage a patient with metastatic NSCLC whose initial mutation testing was limited or results are no longer available?
How do you operationalize finding biomarker information in EHRs/testing portals, either for your own patients or if they have changed providers? If a...
4 Answers available

What are your treatment considerations for a patient with stage IVb NSCLC who is KRAS G12C mutated and PD-L1 high (>50%)?
3 Answers available

How do you approach treatment sequencing in KRAS G12C NSCLC?
Is there evidence or experience to support use of targeted therapy for KRAS G12C mutated NSCLC as first line in place of chemotherapy? 
3 Answers available

Are there best practices for managing or mitigating toxicity from sotorasib such as hyperbilirubinemia or edema?
3 Answers available
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Papers discussed in this category


Lancet Oncol, 2021 Jan 18
First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial.

The New England journal of medicine, 2016-11-10
Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer.

Related Topics in Medical Oncology

  • Lung Cancer
  • Breast Cancer
  • Head and Neck Cancers
  • Hematologic Malignancies
  • Radiation Oncology
  • Gynecologic Oncology
  • Palliation
  • Neuro-Oncology
  • Gastrointestinal Cancers
  • Genitourinary Cancers

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