Pediatric Hematology/Oncology

AYA Cancers

Questions discussed in this category

How do you approach fertility preservation in a young child with cancer?

What is the best way to counsel families in regards to their child's risk of infertility and need for fertility preservation?

2 Answers available

Do you recommend adjuvant radiotherapy for an adult patient with localized myxopapillary ependymoma, WHO Grade 2, status-post gross total resection?

2 Answers available

Do you routinely recommend completion hysterectomy with contralateral salpingo-oophorectomy for patients with a history of fertility-sparing staging for borderline tumor of the ovary who have since completed childbearing?

2 Answers available

Would you consider a cycle of EP in a patient with good risk stage IIIB seminoma on BEP but with bleomycin omitted for cycle 3?

Bleomycin omitted due to asymptomatic decline in DLCO

1 Answer available

What is your approach to treating a young adult with severe aplastic anemia unresponsive to steroids and TPO-mimetics?

What would your next line therapy be? If the patient had no matched related or unrelated donors, would you consider haploidentical transplant?

1 Answer available

What scenario would prophylactic Tocilizumab be considered to prevent Ipilimumab+Nivolumab (immunotherapy) induced toxicity in malignant melanoma?

1 Answer available

How do you decide between RPLND vs. chemotherapy in patients with Stage IIA mixed germ cell tumor as primary treatment?

3 Answers available

How would you approach a sarcoma that was initially diagnosed as UPS of the distal femur with groin lymph node spread, resected, and found to have an EWSR1-FLI1 fusion diagnostic of Ewing's on NGS?

1 Answer available

What is your treatment approach for a pediatric patient with uterine embryonal rhabdomyosarcoma found after removal of a prolapsing uterine mass, with no evidence of distant metastasis on imaging?

1 Answer available

How do you approach hormone replacement therapy for premenopausal patients following pelvic radiation therapy?

How is your approach different from or similar to those who undergo surgical menopause?

1 Answer available

How would you approach an adolescent patient with stage IIIC serous borderline tumor, s/p fertility sparing surgical staging with unilateral salpingo-oophorectromy, who presents with an enlarging contralateral ovarian mass and additional pelvic disease on imaging?

1 Answer available

Papers discussed in this category

Journal of adolescent and young adult oncology, 2020 May 26

Standardizing Risk Assessment for Treatment-Related Gonadal Insufficiency and Infertility in Childhood Adolescent and Young Adult Cancer: The Pediatric Initiative Network Risk Stratification System.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-02-01

Randomized double-blind trial of estrogen replacement therapy versus placebo in stage I or II endometrial cancer: a Gynecologic Oncology Group Study.

Obstet Gynecol, 1998 Oct

Meta-analysis of estrogen therapy in the management of urogenital atrophy in postmenopausal women: second report of the Hormones and Urogenital Therapy Committee.

Acta Oncol, 2019 Apr 08

Sex steroid hormone receptor expression in the vaginal wall in cervical cancer survivors after radiotherapy.

Gynecologic oncology, 1992-11

Long-term follow-up of serous ovarian tumors of low malignant potential.

Cancer, 1998-03-15

Ovarian serous borderline tumors with invasive peritoneal implants.

Cancer, 1998-11-15

Serous borderline tumors of the ovary with noninvasive peritoneal implants.

Cancer, 2004-03-01

Survival among women with borderline ovarian tumors and ovarian carcinoma: a population-based analysis.

Lancet Oncol, 2012 Mar

Borderline ovarian tumour: pathological diagnostic dilemma and risk factors for invasive or lethal recurrence.

Cancer, 1996 Jul 15

Ovarian papillary serous tumors of low malignant potential (serous borderline tumors). A long-term follow-up study, including patients with microinvasion, lymph node metastasis, and transformation to invasive serous carcinoma.

Gynecol Oncol, 2001 Apr

Ultrasound, physical examination, and CA 125 measurement for the detection of recurrence after conservative surgery for early borderline ovarian tumors.

J Clin Oncol, 2001 May 15

Behavior of borderline tumors with particular interest to persistence, recurrence, and progression to invasive carcinoma: a prospective study.

J Clin Oncol, 2007 Jul 10

Management of borderline ovarian neoplasms.

Pediatric blood & cancer, 2018-02

Consensus and controversies regarding the treatment of rhabdomyosarcoma.

J Clin Oncol, 2019 Jun 10

Management of Stage II Germ Cell Tumors: Be Sure, Be Patient, Be Safe.

International journal of radiation oncology, biology, physics, 2009-07-15

The results of surgery, with or without radiotherapy, for primary spinal myxopapillary ependymoma: a retrospective study from the rare cancer network.

International journal of radiation oncology, biology, physics, 2023 Jul 10

Multi-institutional Characterization of Outcomes for Pediatric and Young Adult Patients With High-Risk Myxopapillary Ependymoma After Radiation Therapy.

Pediatric Hematology/Oncology

AYA Cancers

Questions discussed in this category

Papers discussed in this category

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