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Pediatric Oncology
Myelodysplastic Syndromes
Questions discussed in this category
How would you approach cytopenias 5 weeks after initial dosing in a young patient with MDS treated with Azacitadine as a bridge to transplant?
E.g. would you dose-reduce or continue at same dose? Baseline ANC was in the normal range
1 Answer available
Do you routinely send NGS testing from bone marrow samples in patients with unexplained cytopenia or cytoses?
For instance, if clonal hematopoiesis of indeterminate potential (CHIP) suspected
1 Answer available
How would you optimally manage a patient with a MDS/MPN overlap syndrome who has both transfusion-dependent anemia and marked thrombocytosis?
Would this change with someone who has a history of thrombosis (e.g. DVT/PE, MI, CVA)? Would this change with someone who is more fit vs more frail?
1 Answer available
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Papers discussed in this category
American journal of hematology, 2019-04
Refractory anemia with ring sideroblasts (RARS) and RARS with thrombocytosis: "2019 Update on Diagnosis, Risk-stratification, and Management".
Am J Hematol, 2019 Aug 07
The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopenia.
Related Topics in Pediatric Oncology
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Head and Neck Cancers
Hematologic Malignancies
Radiation Oncology
Gynecologic Cancers
Palliation
Neuro-Oncology
Gastrointestinal Cancers
Genitourinary Cancers