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Pulmonology

Allergy & Immunology   

Questions discussed in this category

What approaches can we take to initiate therapy and improve survival rates in patients with HLH?
2 Answers available
Do you avoid use of inhalers with milk protein in patients with a milk allergy?
1 Answer available
Would you use the pneumococcal conjugate-21 vaccine (Capvaxive) instead of the conjugate-20 (Prevnar-20) for routine vaccinations in immunosuppressed patients?
2 Answers available
Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?
4 Answers available
Do you feel high dose Symbicort or Dulera is appropriate to use for SMART despite these doses not being studied in clinical trials?
1 Answer available
When would you recommend prescribing an asthmatic patient budesonide/salbutamol rather than budesonide/formoterol?
2 Answers available
Is methacholine challenge on its way out?
1 Answer available
Is there a role for biologics to improve lung function in patients who have severe asthma with daily symptoms and reduced lung function but do not experience frequent exacerbations?
2 Answers available
Do you give additional pneumococcal vaccines after a dose of PCV20 in patients with asplenia?
1 Answer available
How do you factor smoking history into biologic selection for asthma since the clinical trials generally excluded these patients?
1 Answer available
What factors do you consider prior to offering a trial of ICS/LABA therapy versus a methacholine challenge test in patients with suspected asthma but normal pulmonary function testing?
1 Answer available
Do you diagnose obstruction by the criteria of FEV1/FVC < 70% or < LLN?
5 Answers available
What is your approach to inhaler therapy in a patient with asthma who cannot be on an inhaled corticosteroid due to ocular disease?
1 Answer available
What is your threshold to start triple therapy in mild to moderate asthma/COPD overlap with minimal functional limitation?
1 Answer available
What are best practices in management of severe acute infusion reaction from infliximab?
Patient became acutely flushed, developed severe and prolonged hypotension with brief loss of consciousness, dizziness, nausea, dry heaves and headach...
1 Answer available
Is there a role for biologics to help patients with ABPA who are steroid responsive and have removed their allergen insult, but continue to have an elevated serum IgE and incomplete resolution of symptoms return to their baseline functional status?
1 Answer available
Is there a role for the use of biologics as steroid sparing agents in treating patients with ABPA who are intolerant to prednisone?
1 Answer available
Do you use continuous or intermittent bronchodilator therapy in severe airway obstruction?
1 Answer available
What is your second line therapy for patients with EGPA with mainly pulmonary and sinonasal features who did not respond to mepolizumab 300 mg/month and still require high doses of steroid?
2 Answers available
Is there any PFT criteria that you use in guiding decision making to offer transbronchial lung cryobiopsy to patients with interstitial lung disease?
1 Answer available
Is there a role for biologic therapies in asthma-COPD overlap syndrome with evidence of type 2 inflammation?
2 Answers available
What is your preferred regimen for remission induction and maintenance in EGPA with cardiac involvement?
1 Answer available
Which EGPA patients are most likely to benefit from treatment with anti-IL-5 agents such as mepolizumab?
1 Answer available
Which ANCA vasculitis patients are better candidates for cyclophosphamide rather than rituximab?
2 Answers available
How does your treatment algorithm differ for drug-induced ANCA vasculitis compared to non drug-induced ANCA vasculitis in cases with severe/organ-threatening manifestations?
1 Answer available


Papers discussed in this category

The New England journal of medicine, 2010-07-15
Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis.
Medicine (Baltimore),
The Five-Factor Score revisited: assessment of prognoses of systemic necrotizing vasculitides based on the French Vasculitis Study Group (FVSG) cohort.
The New England journal of medicine, 2010-07-15
Rituximab versus cyclophosphamide for ANCA-associated vasculitis.
The New England journal of medicine, 2017-05-18
Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000-04
Practice guidelines for diseases caused by Aspergillus. Infectious Diseases Society of America.
Chest, 2018 Jan 11
A Randomized Trial of Itraconazole vs Prednisolone in Acute-Stage Allergic Bronchopulmonary Aspergillosis Complicating Asthma.
J Allergy Clin Immunol Pract, 2021 Mar 06
Real-World Effectiveness of Anti-IL-5/5R Therapy in Severe Atopic Eosinophilic Asthma with Fungal Sensitization.
Chest, 2020 Aug 31
Real-World Effectiveness of Benralizumab in Severe Eosinophilic Asthma.
J Allergy Clin Immunol Pract, 2020 Jun 16
Omalizumab Is an Effective Intervention in Severe Asthma with Fungal Sensitization.
Cureus, 2020 Aug 12
Mepolizumab as Possible Treatment for Allergic Bronchopulmonary Aspergillosis: A Review of Eight Cases.
J Allergy Clin Immunol Pract, 2015 Jan 29
Clinical efficacy and immunologic effects of omalizumab in allergic bronchopulmonary aspergillosis.
The American journal of gastroenterology, 2003 Jun
The incidence and management of infusion reactions to infliximab: a large center experience.
The Journal of rheumatology, 2015 Jun 15
Incidence and Management of Infusion Reactions to Infliximab in a Prospective Real-world Community Registry.
Arthritis & rheumatology (Hoboken, N.J.), 2023 Jul 24
The 2022 EULAR/ACR Points to Consider at the Early Stages of Diagnosis and Management of Suspected Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS).
The Journal of allergy and clinical immunology, 2004 Mar
Contamination of dry powder inhalers for asthma with milk proteins containing lactose.
Journal of clinical medicine, 2022 Dec 10
Lactose-Containing Dry-Powder Inhalers for Patients with Cow's Milk Protein Allergy-The Conundrum; A National Survey of Pediatric Pulmonologists and Allergologists.
Lupus, 2014 Jul 30
Serious infections in systemic lupus erythematosus with a focus on pneumococcal infections.
MMWR. Morbidity and mortality weekly report, 2024 Sep 12
Use of 21-Valent Pneumococcal Conjugate Vaccine Among U.S. Adults: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024.
Journal of the Endocrine Society, 2022 Dec 02
Perioperative Evaluation and Management of Patients on Glucocorticoids.
Diagnostics (Basel, Switzerland), 2021 Apr 20
Glucocorticoid Withdrawal-An Overview on When and How to Diagnose Adrenal Insufficiency in Clinical Practice.

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