Questions discussed in this category
How do you view it relative to existing options like TNFi, IL-23, or IL-17s like ixekizumab?
For example, in patients with many swollen/tender joints, enthesitis, nail involvement do you expect particularly good response? Are there patients in...
How will you counsel patients about the risk and what strategies will you use to mitigate the increased risk of fungal infections see in the BE COMPLE...
The patient has ongoing inflammatory arthritis despite methotrexate, apremilast, and jak inhibitor trials.
Is there any concern for drug interactions of DMARDs and/or biologics with anti seizure medications?
Given the drug-drug interaction, do you monitor more closely for methotrexate toxicity, counsel on symptoms of methotrexate toxicity, or avoid the com...
What side effects do you highlight in conversation with them? How do you approach toxicity monitoring?
What imaging modality would be most helpful?
Assuming no symptoms of TB, should patients be treated for latent TB prior to starting TNF inhibitors or other immunosuppressive agents?
Patient is on antibiotics for chronic spinal hardware infection.
In contrast to TNF inhibitors for psoriatic arthritis, which seem to peak and maintain response percentages, the DISCOVER-2 Trial (McInnes et al., PMI...
In clinical practice continued steroid dependence is often seen as a reason to switch therapy and providers can be especially hesitant to use systemic...
Based on the results of the DISCOVER-2 Trial (McInnes et al., PMID 34719872), should guselkumab be used prior to anti-TNF therapy in these patients?
In patients refractory to NSAIDs and sulfasalazine
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Papers discussed in this category
Arthritis Rheumatol, 2019 Jan
Ann. Rheum. Dis., 2019 Sep 28
Lancet,
Arthritis & rheumatology (Hoboken, N.J.), 2016-05
Arthritis Rheumatol, 2019 Oct
Rheumatology (Oxford),
Rheumatology (Oxford),
Clin. Exp. Rheumatol., 2016 Dec 13
Lancet, 2015 Oct 01
J Rheumatol Suppl,
Nat Rev Rheumatol,
Rheumatology (Oxford),
Ann Rheum Dis, 2015 Dec 07
J Med Imaging Radiat Oncol,
J Ultrason, 2016 Mar 29
Annals of the rheumatic diseases, 2017-04
Arthritis Care Res (Hoboken), 2018 Aug
Arthritis Care Res (Hoboken),
Journal of clinical medicine, 2022 Apr 21
Clinical and experimental rheumatology, 2020 Feb 11
Journal of clinical medicine, 2021 Dec 29
Clinical and experimental rheumatology, 2022 Mar 01
Curr Med Chem,
Pathology, 2017 Mar 11
Arthritis Care Res (Hoboken), 2019 Jan
Arthritis Rheumatol, 2022 Feb 07
Annals of internal medicine, 2018-01-16
J Immunother Cancer,
Rheumatology (Oxford), 2014 Sep 16
The Journal of rheumatology, 2012-01
JAAD Case Rep, 2019 Oct 10
Clinical rheumatology, 1988 Sep
Journal of the American Academy of Dermatology, 1987 Apr
Journal of the American Academy of Dermatology, 2020 May 19
Annals of the rheumatic diseases, 2018-09
Arthritis & rheumatology (Hoboken, N.J.), 2019-02
RMD open, 2020 Feb
The New England journal of medicine, 2014 Jun 05
Trials, 2022 Sep 05
Annals of the rheumatic diseases, 2024 Mar 18
Ann Rheum Dis, 2020 Dec 17
The Journal of rheumatology, 1997 May
British journal of rheumatology, 1995 May
Expert review of anticancer therapy, 2009-01
Lancet Gastroenterol Hepatol, 2023 Feb 01