Pediatric Hematology/Oncology

ITP

Questions discussed in this category

What is your approach to an infant (<12 mo) with new onset petechiae and thrombocytopenia, with labs consistent with ITP?

Initial labs obtained? Factors to consider when deciding admission vs outpatient management? Threshold for treatment? Treatment with steroids vs ...

1 Answer available

How do you choose between therapies for newly diagnosed ITP that is refractory to steroids and IVIG?

Received dexamethasone 40 mg daily x4 and IVIG without response. No DIC. PB flow cytometry and bone marrow biopsy without pathology. Are there specifi...

1 Answer available

What are your top takeaways in Classical Hematology from ASH 2024?

9 Answers available

How do you approach an ITP patient who responds very well to steroids but the response is short-lived?

How would you counsel the patient if he/she wants to continue on steroids?

3 Answers available

How do you approach very treatment-refractory ITP?

Such as the case in which a patient is unresponsive to steroids, IVIG, TPO-agonist, rituximab, splenectomy, and even fostamitinib.

1 Answer available

Based on recent data would you consider adding ATRA to low dose rituximab for steroid refractory ITP?

Wu et al., PMID 34665865

1 Answer available

At what platelet count would you feel comfortable dosing aspirin 81 mg for coronary artery disease in a patient with ITP?

Presuming strong indication for ASA - eg history of NSTEMI

1 Answer available

For treatment of ITP, what would you add to dexamethasone to achieve the fastest recovery in a patient waiting for a procedure?

IVIG, TPO, or other agents?

1 Answer available

Are there any reasons to consider a prolonged course of steroids with taper over a shorter course of pulsed steroids in the treatment of ITP?

For example, do we prefer one regimen over the other in patients with a bleeding history or who have relapsed after a lengthy remission?

1 Answer available

When (if ever) do you check for anti-platelet antibodies for workup of thrombocytopenia?

1 Answer available

Papers discussed in this category

The New England journal of medicine, 2013-02-21

Apixaban for extended treatment of venous thromboembolism.

The New England journal of medicine, 2017 Mar 18

Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism.

Pediatric Hematology/Oncology

ITP

Questions discussed in this category

Papers discussed in this category

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