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Premenopausal   

Questions discussed in this category


In the current era of adjuvant CDK4/6 inhibitor use for high-risk HR+/HER2-negative breast cancer, what is the preferred adjuvant chemotherapy regimen for premenopausal women — AC-T or TC?
1 Answer available

Do you check AMH levels to decide on adjuvant chemotherapy in premenopausal patients with node-positive ER+ breast cancer?
Did the ASCO 2024 presentation from RxPONDER change your practice?
1 Answer available

Would you consider anthracycline based neoadjuvant therapy for ER negative, HER2 positive inflammatory breast cancer in a premenopausal female given the subset not adequately represented in non-anthracycline regimen trials?
3 Answers available
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Papers discussed in this category


Lancet Oncol., 2018 Nov 06
Neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2 blockade for HER2-positive breast cancer (TRAIN-2): a multicentre, open-label, randomised, phase 3 trial.

Lancet (London, England), 2014-06-21
Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials.

J. Clin. Oncol., 2020 Sep 20
Abemaciclib Combined With Endocrine Therapy for the Adjuvant Treatment of HR+, HER2-, Node-Positive, High-Risk, Early Breast Cancer (monarchE).

The New England journal of medicine, 2024 Mar 21
Ribociclib plus Endocrine Therapy in Early Breast Cancer.

Related Topics

  • Breast Cancer
  • Medical Oncology
  • Breast Cancer, Non-metastatic
  • HER2+
  • Micrometastatic
  • ASCO 2024
  • HER+
  • pertuzumab

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