For primary CNS lymphoma, when do you refer for whole brain radiation therapy (WBRT)?

Topics: Hematologic Malignancies • Radiation Oncology • Medical Oncology • Lymphoma • Hematology

My experience has been that patients can be neurologically devastated years out from WBRT. In Medical Oncology practice at my institution, we do not refer to Radiation Oncology for WBRT as consolidation treatment, and I was surprised to find this recommendation in NCCN guidelines.

Answer from: Medical Oncologist at Academic Institution

When data are limited, consensus guidelines tend to rely on the personal clinical experiences of the guideline committee members. That may explain the NCCN guidelines. Recently, remarkable progress has been noted in the treatment of CNS lymphoma with drugs alone. Ibrutinib is particularly effective ...

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Radiation Oncologist at Center for Neurosciences
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