How do you manage a large surgical cavity following resection of a melanoma brain metastasis?

I've used 30 Gy in 5 fx before for a cerebellar melanoma cavity about 4.5x3 cm. It's much less likely to cause necrosis and edema than single fx. There may be some local enhancement of IO response.

Regarding immunotherapy, I don't give steroids unless symptoms occur, and try to keep it to no more th...