How do you manage anticoagulation for patients with DVT/PE who have brain metastases?  

Some medical oncologists tend to hold anticoagulation in patients who develop brain metastases for fear of causing intracranial hemorrhage.  Is there any data to support this?  In your field, e.g. melanoma, NSCLC, breast, are there specific considerations to take into account?  Would radiation treatments (either SRS or WBRT) be an indication to hold anticoagulation?  



Answer from: Radiation Oncologist at Community Practice

Answer from: Radiation Oncologist at Academic Institution

Answer from: Medical Oncologist at Academic Institution